Sun Sep 20, 8:20 PM ET · NBC · GEHA Field at Arrowhead Stadium, Kansas City Primetime Upcoming · Fri 8:20 PM
Indianapolis Colts
0-1 · 6-10 last season
Implied20.5
At KC -6.5 Total 47.5 Live line · IND +270 · KC -335
Kansas City Chiefs
1-0 · 7-9 last season
Implied27.0
Line movement open Sep 15 KC spread -6.5 -6.5 no move Total 47.5 47.5 no move FanDuel

IND @ KC: the angle lands Fri 8:20 PM

Lines, matchups, injuries and forecast below are live now.

Key matchups

TeamPlayerPos ProjDK $ vs defenseFPAEdge
KC Kenneth Walker III RB 17.5 $6,500 IND #25 of 32 25.1 Favorable
KC Patrick Mahomes QB 16.8 $5,500 IND #27 of 32 20.7 Smash
KC Rashee Rice WR 15.4 $6,500 IND #31 of 32 38.1 Smash
KC Travis Kelce TE 11.2 $4,000 IND #23 of 32 14.8 Favorable
IND skill positions vs KC defense
QB
#3/32
14.3 fpa
Avoid
RB
#3/32
18.0 fpa
Avoid
WR
#4/32
25.5 fpa
Avoid
TE
#12/32
12.5 fpa
Bad
KC skill positions vs IND defense
QB
#27/32
20.7 fpa
Elite
RB
#25/32
25.1 fpa
Elite
WR
#31/32
38.1 fpa
Elite
TE
#23/32
14.8 fpa
Good

Rank 32 allows the most fantasy points to the position (softest matchup), 1 the fewest. Ratings blend the 2025-26 regular season (with a last-8-games form tilt) into current-season data as games are played: current weight = games / (games + 4), so the new season takes over quickly.

Game script & scoring

Projected points (market implied)
IND20.5
KC27.0
Offense profile
INDRank of 32KC
26.7 #8 Pts / G 22.2 #18
229.4 #16 Pass yds / G 232.2 #15
111.3 #21 Rush yds / G 113.3 #19
58.4 #27 Plays / G 63.3 #11
57% Pass rate 56%
1.5 Pass TD / G 1.4
1.6 Rush TD / G 0.9
1.8 Sacks taken / G 2.8
0.9 INT thrown / G 0.8
Defense profile
INDRank of 32KC
26.1 #26 Pts allowed / G 18.2 #3
277.6 #32 Pass yds allowed 200.0 #6
108.6 #9 Rush yds allowed 102.9 #5
2.4 Sacks / G 2.1
0.7 INT / G 0.7
1.3 Pass TD allowed 1.0
1.2 Rush TD allowed 0.8

Rank 1 = best of 32 (offense: most; defense: fewest allowed). Basis: rolling window from 2025-09-15, 20 games per team.

Weather

Kickoff forecast posts within 3 days of kickoff. (GEHA Field at Arrowhead Stadium, Kansas City)

DFS

KC projected players
PosPlayerProj Floor / ceilDK $Val FD $vs
RB Kenneth Walker III 17.5 10.4 / 28.8 $6,500 2.69x $7,500 #25
QB Patrick Mahomes 16.8 10.8 / 26.6 $5,500 3.05x $7,900 #27
WR Rashee Rice 15.4 8.3 / 28.5 $6,500 2.37x $7,600 #31
TE Travis Kelce 11.2 5.2 / 21.6 $4,000 2.79x $5,500 #23
WR Xavier Worthy 9.2 3.3 / 16.4 $4,500 2.05x $6,200 #31
RB Emmett Johnson 4.6 1.9 / 11.3 $4,500 1.02x $4,400 #25
WR Tyquan Thornton 3.9 0.0 / 10.6 $3,500 1.11x $5,000 #31

Val = projected points per $1,000 of DraftKings salary. vs = the opposing defense's rank against that position (32 softest).

Injuries

IND 6 listed
  • IR Carson Towt TE Unknown Severe
  • IR D.J. Montgomery WR Abdomen Severe
  • IR Will Mallory TE Thumb Severe
  • Out Austin Ajiake LB Hamstring Minimal
  • Quest. Alec Pierce WR Unknown Minimal
  • IR Cameron Mitchell CB Unknown Minimal
KC 6 listed
  • Out Jeff Caldwell WR Knee Severe
  • IR John Michael Gyllenborg TE Knee Severe
  • Out Chamarri Conner FS Knee Minimal
  • Out Josh Simmons OT Back Minimal
  • IR Ethan Downs DE Downs Minimal
  • IR Matt Waletzko OT Undisclosed Minimal
Full NFL injury report

Week 2 slate

Swipe for all 16 games this week.
Updated Sep 15, 9:27 AM ET For entertainment and informational purposes only; not betting or gambling advice.