Sun Oct 11, 4:25 PM ET · FOX · Lumen Field, Seattle Division Upcoming · Fri 4:25 PM
San Francisco 49ers
4-0 · 4-0 last season
Implied21.8
At SEA -3 Total 46.5 Live line · SF +146 · SEA -174
Seattle Seahawks
3-1 · 3-1 last season
Implied24.8
Line movement open Oct 6 SEA spread -3 -3 no move Total 47.5 46.5 1.0 FanDuel

SF @ SEA: the angle lands Fri 4:25 PM

Lines, matchups, injuries and forecast below are live now.

Key matchups

TeamPlayerPos ProjDK $ vs defenseFPAEdge
SF Christian McCaffrey RB 20.7 $8,200 SEA #10 of 32 20.1 Neutral
SF Brock Purdy QB 16.7 $6,500 SEA #2 of 32 14.0 Tough
SF George Kittle TE 15.3 $5,200 SEA #11 of 32 12.4 Neutral
SF Mike Evans WR 14.0 $6,500 SEA #1 of 32 23.5 Tough
SEA Jaxon Smith-Njigba WR 23.3 $8,800 SF #11 of 32 29.8 Neutral
SEA Sam Darnold QB 15.9 $5,800 SF #8 of 32 16.4 Neutral
SEA Emanuel Wilson RB 12.7 $5,300 SF #26 of 32 24.7 Smash
SEA AJ Barner TE 8.0 $3,200 SF #12 of 32 12.5 Neutral
SF skill positions vs SEA defense
QB
#2/32
14.0 fpa
Avoid
RB
#10/32
20.1 fpa
Bad
WR
#1/32
23.5 fpa
Avoid
TE
#11/32
12.4 fpa
Bad
SEA skill positions vs SF defense
QB
#8/32
16.4 fpa
Avoid
RB
#26/32
24.7 fpa
Elite
WR
#11/32
29.8 fpa
Bad
TE
#12/32
12.5 fpa
Bad

Rank 32 allows the most fantasy points to the position (softest matchup), 1 the fewest. Ratings blend the 2025-26 regular season (with a last-8-games form tilt) into current-season data as games are played: current weight = games / (games + 4), so the new season takes over quickly.

Game script & scoring

Projected points (market implied)
SF21.8
SEA24.8
Offense profile
SFRank of 32SEA
30.5 #3 Pts / G 26.2 #11
251.8 #13 Pass yds / G 249.0 #15
137.2 #6 Rush yds / G 110.2 #13
57.0 #29 Plays / G 59.2 #23
49% Pass rate 51%
2.8 Pass TD / G 2.5
1.2 Rush TD / G 0.8
0.0 Sacks taken / G 1.5
0.2 INT thrown / G 0.8
Defense profile
SFRank of 32SEA
16.0 #3 Pts allowed / G 18.2 #5
215.5 #9 Pass yds allowed 161.2 #2
99.8 #9 Rush yds allowed 102.0 #12
1.5 Sacks / G 2.8
0.2 INT / G 1.5
1.0 Pass TD allowed 1.5
0.5 Rush TD allowed 0.2

Rank 1 = best of 32 (offense: most; defense: fewest allowed). Basis: rolling window from 2026-09-09, 4 games per team.

Weather

Kickoff forecast posts within 3 days of kickoff. (Lumen Field, Seattle)

DFS

SF projected players
PosPlayerProj Floor / ceilDK $Val FD $vs
RB Christian McCaffrey 20.7 12.5 / 29.7 $8,200 2.52x $8,400 #10
QB Brock Purdy 16.7 11.0 / 25.8 $6,500 2.58x $8,300 #2
TE George Kittle 15.3 7.1 / 24.1 $5,200 2.94x $6,700 #11
WR Mike Evans questionable 14.0 6.3 / 23.0 $6,500 2.16x $7,100 #1
WR Deebo Samuel Sr. 11.5 4.9 / 18.0 $5,500 2.09x $6,900 #1
RB Kaelon Black questionable 3.2 1.0 / 8.0 $4,700 0.69x $5,000 #10
WR Jordan Watkins 2.8 0.0 / 7.7 $3,000 0.93x $5,100 #1
SEA projected players
PosPlayerProj Floor / ceilDK $Val FD $vs
WR Jaxon Smith-Njigba 23.3 12.1 / 34.6 $8,800 2.65x $9,300 #11
QB Sam Darnold 15.9 10.4 / 24.8 $5,800 2.75x $7,200 #8
RB Emanuel Wilson 12.7 6.8 / 20.3 $5,300 2.39x $6,000 #26
TE AJ Barner 8.0 2.6 / 14.0 $3,200 2.50x $4,800 #12
WR Rashid Shaheed 7.6 2.1 / 14.0 $4,000 1.91x $5,000 #11
RB George Holani questionable 7.2 3.1 / 12.4 $4,500 1.60x $4,900 #26
WR Cooper Kupp 6.6 1.7 / 12.7 $3,800 1.74x $5,300 #11

Val = projected points per $1,000 of DraftKings salary. vs = the opposing defense's rank against that position (32 softest).

Build this slate in the optimizer See player props

Props

PlayerMarketLine ProjOverBookOpp rank
Jaxon Smith-Njigba WR SEA Receptions 6.5 5.9 +125 BetMGM #9
Jaxon Smith-Njigba WR SEA Rec yds 92.5 89.1 -113 DraftKings #9
Christian McCaffrey RB SF Rush yds 53.5 60.9 -114 DraftKings #11
Christian McCaffrey RB SF Receptions 4.5 4.5 -125 FanDuel #2
Christian McCaffrey RB SF Rec yds 36.5 34.1 -111 DraftKings #2
Brock Purdy QB SF Pass TD 1.5 1.8 +111 DraftKings #14
Brock Purdy QB SF Pass yds 226.5 166.1 +100 BetMGM #2
Brock Purdy QB SF Rush yds 22.5 20.1 -107 DraftKings #11
Sam Darnold QB SEA Pass TD 1.5 2.0 -102 DraftKings #3
Sam Darnold QB SEA Pass yds 225.5 187.8 -111 DraftKings #9
Sam Darnold QB SEA Rush yds 4.5 3.7 -110 BetMGM #9
George Kittle TE SF Receptions 4.5 3.8 -106 FanDuel #2
George Kittle TE SF Rec yds 53.5 57.9 -110 DraftKings #2
Mike Evans WR SF Receptions 3.5 4.1 +120 BetMGM #2

Best available over price per line. Opp rank = the defense's rank in that stat allowed (32 allows the most).

All SF and SEA props with AI grades

Injuries

SF 8 listed
  • Out Isaac Guerendo RB Pectoral Severe
  • Out Ricky Pearsall WR Unknown Severe
  • Out Andrew Farmer DE Back Minimal
  • Out Mikail Kamara DE Knee Minimal
  • Out Nick Zakelj G Undisclosed Minimal
  • Quest. James Thompson Jr. DT Unknown Minimal
  • Quest. Kyle Juszczyk FB Unknown Minimal
  • Quest. Marques Sigle FS High-Ankle Minimal
SEA 8 listed
  • IR Irvin Charles WR Undisclosed Severe
  • IR Jadarian Price RB Chest Severe
  • IR Jake Bobo WR Knee Severe
  • IR Zach Charbonnet RB Knee Severe
  • Out Robbie Ouzts FB Unknown Minimal
  • Out Terrion Arnold CB Unknown Minimal
  • Quest. Chazz Surratt LB Unknown Minimal
  • Quest. Leonard Williams DE Ankle Minimal
Full NFL injury report

Week 5 slate

Swipe for all 15 games this week.
TB @ DAL
Thu 8:15 PM ET
DAL -8.5
O/U 48.5
Ready
PHI @ JAX
Sun 9:30 AM ET
JAX -7.5
O/U 41.5
Unlocks Fri 9:30 AM
CHI @ GB
Sun 1:00 PM ET
CHI -1.5
O/U 45.5
Unlocks Fri 1:00 PM
CIN @ MIA
Sun 1:00 PM ET
CIN -6.5
O/U 43.5
Unlocks Fri 1:00 PM
CLE @ NYJ
Sun 1:00 PM ET
NYJ -1.5
O/U 39.5
Unlocks Fri 1:00 PM
HOU @ TEN
Sun 1:00 PM ET
HOU -7.5
O/U 37.5
Unlocks Fri 1:00 PM
IND @ PIT
Sun 1:00 PM ET
PIT -2.5
O/U 44.5
Unlocks Fri 1:00 PM
LV @ NE
Sun 1:00 PM ET
NE -3.5
O/U 44.5
Unlocks Fri 1:00 PM
MIN @ NO
Sun 1:00 PM ET
MIN -1.5
O/U 42.5
Unlocks Fri 1:00 PM
NYG @ WAS
Sun 1:00 PM ET
WAS -3.5
O/U 42.5
Unlocks Fri 1:00 PM
DEN @ LAC
Sun 4:05 PM ET
DEN -3.5
O/U 42.5
Unlocks Fri 4:05 PM
DET @ ARI
Sun 4:25 PM ET
DET -5.5
O/U 54.5
Unlocks Fri 4:25 PM
SF @ SEA
Sun 4:25 PM ET
SEA -3
O/U 46.5
Unlocks Fri 4:25 PM
BAL @ ATL
Sun 8:20 PM ET
ATL -3.5
O/U 43.5
Unlocks Fri 8:20 PM
BUF @ LA
Mon 8:15 PM ET
LA -3.5
O/U 54.5
Unlocks Sat 8:15 PM
Updated Oct 8, 5:07 PM ET For entertainment and informational purposes only; not betting or gambling advice.