Archived Week 1 breakdown.
The odds, projections and picks below are the pregame numbers as published in 2026, not a live board.
See this week's breakdowns
Thu Sep 10, 8:35 PM ET · NETFLIX · Melbourne Cricket Ground, Melbourne, Australia
Neutral site Division Final
San Francisco 49ers
0-0 · 13-6 last season
Final27
Neutral site
LA -3.5 Total 47.5 SF covered · Under
Los Angeles Rams
0-0 · 13-7 last season
Final7
Line movement open Sep 6
LA spread
-3.5 -3.5
no move
Total
48.5 47.5
1.0
The angle, before kickoff
Pass · 3/10
LA -3.5 with implied 26-22.5, but the margin sits exactly on the number.
SidePASSimplied margin 3.5 sits exactly on the -3.5 spread at a neutral site.
TotalPASSDraftEdge projected total lands on the 48.5 line.
Best bet
Puka Nacua over 7.5 receptions, a 22.9-projected target hog against SF's #21 WR defense.
Quick hits
- Market: LA -3.5, total 48.5, implied LA 26.0 / SF 22.5.
- Balanced-to-high: LA's #1 offense (30.8 pts) against SF's #18 defense.
- Puka Nacua vs SF #21 WR defense is the decisive edge, 22.9 projected.
- LA leads and stays balanced (57% pass); SF throws to chase, McCaffrey key.
- SF WR room thin with Pearsall out; leans on McCaffrey and Kittle.
Key matchups
- Colby Parkinson vs SF #26 TE defense: 16.0 fpa, smash spot, cheap at $3500.
- Puka Nacua vs SF #21 WR defense: 32.5 fpa, favorable, 22.9 projected.
- Kyren Williams vs SF #24 RB defense: 24.5 fpa, favorable run funnel.
- Mike Evans vs LA #23 WR defense: 34.6 fpa, favorable but only 10.9 projected.
- McCaffrey vs LA #16 RB defense: 22.2 fpa, neutral, still 22.0 projected.
- Brock Purdy vs LA #16 QB defense: 16.9 fpa, neutral, 18.4 projected.
QB
#19/32
17.9 fpa
RB
#13/32
22.1 fpa
WR
#29/32
37.2 fpa
TE
#8/32
11.6 fpa
QB
#9/32
15.9 fpa
RB
#21/32
24.5 fpa
WR
#13/32
29.9 fpa
TE
#21/32
14.1 fpa
Rank 32 allows the most fantasy points to the position (softest matchup), 1 the fewest. Ratings blend the 2025-26 regular season (with a last-8-games form tilt) into current-season data as games are played: current weight = games / (games + 4), so the new season takes over quickly.
Game script & scoring
- LA runs 65 plays (#3) at 57% pass; SF 63 plays at 55%.
- LA favored, controls script; SF trails and leans pass with McCaffrey outlet.
- Points split near 26-22.5; LA's 2.7 pass TD rate drives red-zone edge.
Projected points (market implied)
SF22.0
LA25.5
Offense profile
SFRank of 32LA
25.1
#11
Pts / G
29.6
#1
246.5
#8
Pass yds / G
278.6
#1
108.2
#23
Rush yds / G
127.2
#8
62.7
#15
Plays / G
64.6
#4
55%
Pass rate
56%
1.9
Pass TD / G
2.6
0.8
Rush TD / G
1.0
1.5
Sacks taken / G
1.3
0.9
INT thrown / G
0.5
Defense profile
SFRank of 32LA
22.4
#14
Pts allowed / G
22.2
#12
233.4
#19
Pass yds allowed
243.7
#23
115.1
#14
Rush yds allowed
113.1
#12
1.2
Sacks / G
2.4
0.4
INT / G
1.0
1.6
Pass TD allowed
1.8
0.9
Rush TD allowed
0.6
Rank 1 = best of 32 (offense: most; defense: fewest allowed). Basis: rolling window from 2025-09-14, 21 games per team.
Weather
At kickoff · 2026-09-11 11:00 local
No weather factor
Conditions
Sunny
Temp
59°F
feels 55°
Wind
3 mph S
gusts 3 mph
Rain
2%
0.00 in
Humidity
49%
- Sunny, 59F, wind 3 mph: no weather factor
WeatherAPI hourly forecast · Grass surface
- Sunny, 59F, wind 4 mph, 2% rain: no weather factor.
- Passing and kicking unaffected; totals and DFS clean.
DFS
- Stack: Stafford with Nacua, LA's #1 offense into a soft SF WR spot.
- Value: Parkinson $3500 (1.82x) vs #26 TE defense, punt-priced smash.
- Fade: Mike Evans $6100 at 1.79x, favorable matchup but only 10.9 projected.
- Contrarian: Kyren Williams $6200 as run funnel against #24 SF RB defense.
Val = projected points per $1,000 of DraftKings salary. vs = the opposing defense's rank against that position (32 softest).
Props
- Colby Parkinson - receptions o2.5 (+140) - lean over - #26 TE matchup, 6.4 projected.
- Puka Nacua - receptions o7.5 (+120) - lean over - 22.9 projection vs #21 defense.
- Kyren Williams - rushing yards o55.5 (+155) - lean over - favorable #24 RB spot.
- McCaffrey - receptions o4.5 (-118) - lean over - SF pass-heavy trailing script.
Injuries
- Out Jordan James RB Coach'S Decision Severe
- Out Jordan Watkins WR Coach'S Decision Severe
- Out Kurtis Rourke QB Unknown Severe
- Out Ricky Pearsall WR Unknown Severe
- Out Andrew Farmer DE Back Minimal
- Out Enrique Cruz Jr. OT Unknown Minimal
- Out Ephesians Prysock CB Coach'S Decision Minimal
- Out Mikail Kamara DE Knee Minimal
- Out CJ Daniels WR Coach'S Decision Severe
- Out Max Klare TE Coach'S Decision Severe
- Out Tutu Atwell WR Coach'S Decision Severe
- Out Ty Simpson QB Unknown Severe
- Out Bill Murray DT Unknown Minimal
- Out Daniel Rickert DE Knee Minimal
- Out Eddie Walls III LB Undisclosed Minimal
- Out Myles Garrett LB Unknown Minimal
Trends & head-to-head
- LA won last meeting 42-26 on 2025-11-09; SF won 26-23 before that.
- LA 3-2 last five; SF 3-2 last five with wide swings.
- Line static: spread -3.5 and total 48.5 unmoved since open.
W 27-7 @ LAL 6-41 @ SEAW 23-19 @ PHIL 3-13 vs SEAW 42-38 vs CHI
L 7-27 vs SFL 27-31 @ SEAW 20-17 @ CHIW 34-31 @ CARW 37-20 vs ARI
Head-to-head
- Sep 10, 2026 SF 27 at LA 7
- Nov 9, 2025 LA 42 at SF 26
- Oct 2, 2025 SF 26 at LA 23
Watch list
- Jaylen Watson (CB, Questionable, toe): his status shifts SF's WR value.
- Kyle Juszczyk (FB, Questionable, finger): monitor SF backfield roles.
- Line at -3.5: any move off the key number changes the side read.
- Pearsall out already: confirm SF WR snap distribution pre-kick.
Week 1 slate
Swipe for all 16 games this week.
Wed 8:20 PM ET
SEA -3.5
O/U 44.5
Final
Thu 8:35 PM ET
LA -3.5
O/U 47.5
Final
Sun 1:00 PM ET
PIT -5.5
O/U 40.5
Final
Sun 1:00 PM ET
BAL -3.5
O/U 47.5
Final
Sun 1:00 PM ET
BUF -1.5
O/U 44.5
Final
Sun 1:00 PM ET
CHI -3
O/U 47.5
Final
Sun 1:00 PM ET
JAX -8.5
O/U 40.5
Final
Sun 1:00 PM ET
DET -6.5
O/U 49.5
Final
Sun 1:00 PM ET
TEN -1.5
O/U 38.5
Final
Sun 1:00 PM ET
CIN -3.5
O/U 50.5
Final
Sun 4:25 PM ET
LAC -9.5
O/U 47.5
Final
Sun 4:25 PM ET
MIN -1.5
O/U 46.5
Final
Sun 4:25 PM ET
LV -3
O/U 39.5
Final
Sun 4:25 PM ET
PHI -5.5
O/U 44.5
Final
Sun 8:20 PM ET
DAL -3
O/U 47.5
Final
Mon 8:15 PM ET
KC -2.5
O/U 42.5
Kicked off